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Year Number of Results
2003 2
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2012 1
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Page 1
Signalling, sorting and scaffolding adaptors for Toll-like receptors.
Luo L, Lucas RM, Liu L, Stow JL. Luo L, et al. J Cell Sci. 2019 Dec 30;133(5):jcs239194. doi: 10.1242/jcs.239194. J Cell Sci. 2019. PMID: 31889021 Review.
So far, seven proximal TLR adaptors have been identified: MyD88, MAL, TRIF (also known as TICAM1), TRAM (TICAM2), SARM (SARM1), BCAP (PIK3AP1) and SCIMP. Most adaptors tether directly to TLRs through homotypic Toll/interleukin-1 receptor domain (TIR)-TIR interaction …
So far, seven proximal TLR adaptors have been identified: MyD88, MAL, TRIF (also known as TICAM1), TRAM (TICAM2), SARM (SARM1) …
Evidence for evolving Toll-IL-1 receptor-containing adaptor molecule function in vertebrates.
Sullivan C, Postlethwait JH, Lage CR, Millard PJ, Kim CH. Sullivan C, et al. J Immunol. 2007 Apr 1;178(7):4517-27. doi: 10.4049/jimmunol.178.7.4517. J Immunol. 2007. PMID: 17372010
In mammals, Toll-IL-1R-containing adaptor molecule 1 (TICAM1)-dependent TLR pathways induce NF-kappaB and IFN-beta responses. ...Comparative genome analysis suggests that TICAM1 and TICAM2 evolved from a common vertebrate TICAM ancestor following a gene dupli …
In mammals, Toll-IL-1R-containing adaptor molecule 1 (TICAM1)-dependent TLR pathways induce NF-kappaB and IFN-beta responses. ...Comp …
Signalling of toll-like receptors.
Brikos C, O'Neill LA. Brikos C, et al. Handb Exp Pharmacol. 2008;(183):21-50. doi: 10.1007/978-3-540-72167-3_2. Handb Exp Pharmacol. 2008. PMID: 18071653 Review.
Characterization of bbtTICAM from amphioxus suggests the emergence of a MyD88-independent pathway in basal chordates.
Yang M, Yuan S, Huang S, Li J, Xu L, Huang H, Tao X, Peng J, Xu A. Yang M, et al. Cell Res. 2011 Oct;21(10):1410-23. doi: 10.1038/cr.2011.156. Epub 2011 Sep 20. Cell Res. 2011. PMID: 21931360 Free PMC article.
The protein architecture of bbtTICAM is similar to that of vertebrate TICAM1 (TIR-containing adaptor molecule-1, also known as TRIF), while phylogenetic analysis based on the TIR domain indicated that bbtTICAM is the oldest ortholog of vertebrate TICAM1 and TICAM …
The protein architecture of bbtTICAM is similar to that of vertebrate TICAM1 (TIR-containing adaptor molecule-1, also known as TRIF), …
A genome-wide search of Toll/Interleukin-1 receptor (TIR) domain-containing adapter molecule (TICAM) and their evolutionary divergence from other TIR domain containing proteins.
Verma S, Sowdhamini R. Verma S, et al. Biol Direct. 2022 Sep 2;17(1):24. doi: 10.1186/s13062-022-00335-9. Biol Direct. 2022. PMID: 36056415 Free PMC article.
., TIR domain-containing adapter-inducing interferon-beta (TRIF/TICAM1) and TIR domain containing adaptor molecule2 (TRAM/TICAM2), by using computational approaches. ...Our study also adds a timeframe to infer the duplication of TICAM protein from Leptocardii and la …
., TIR domain-containing adapter-inducing interferon-beta (TRIF/TICAM1) and TIR domain containing adaptor molecule2 (TRAM/TICAM2 …
Can TRIF/TICAM-1 Dependent Pathway be Target Pathway in Lumbar Intervertebral Disc Degeneration?
Alizada O, Akyol S, Ozlen F, Akgun MY, Cetintas SC, Turk O, Hanci M. Alizada O, et al. Turk Neurosurg. 2023;33(5):804-810. doi: 10.5137/1019-5149.JTN.42287-22.2. Turk Neurosurg. 2023. PMID: 36951033 Free article.
Levels of all adaptor molecules were highest in the MC I group and lowest in the MC III group. The levels of IRF3, TICAM1, TICAM2, NF-kB p65, TRAF6, and TLR4 were significantly increased in the MC I group compared to the MC II and MC III groups. ...
Levels of all adaptor molecules were highest in the MC I group and lowest in the MC III group. The levels of IRF3, TICAM1, TICAM2 …
35 results